Healing From Grief & Loss | Dr. Mary-Frances O'Connor
My guest is Dr. Mary-Frances O’Connor, PhD, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss.
June 2, 2025
2 hr 34 min
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Episode 231 · June 2, 2025
Healing From Grief & Loss | Dr. Mary-Frances O'Connor
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Healing From Grief & Loss | Dr. Mary-Frances O'Connor
Summary
My guest is Dr. Mary-Frances O’Connor, PhD, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss. We discuss what happens in the brain and body when we grieve, the role of dopamine and yearning in the grieving process, the health risks of getting stuck at particular stages of grief and how to move through loss while also deeply honoring the person, animal or thing that is no longer with us. Dr. O’Connor explains that grief involves cycling back and forth between protest and despair (often guilt and anger too) and explains science-supported ways to move through that process in the healthiest possible way. Everyone experiences grief and loss at some point. Dr. O’Connor provides valuable knowledge and tools to help you navigate grief under any circumstance.
Read the episode show notes at hubermanlab.com.
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Timestamps
00:00:00 Mary-Frances O’Connor
00:02:22 Grief vs Grieving; Love & Bonding, Gone Yet Everlasting
00:07:42 Sponsors: Wealthfront & BetterHelp
00:10:29 Sudden vs Slow Death, Attachment, Reframing Relationship
00:14:52 Religion, Integrating the New Relationship
00:20:46 Yearning, Dopamine, Brain, Addiction
00:27:58 Culture & Grief Literacy; Protest, Despair & Hope, New Relationships
00:40:09 Sponsors: AG1 & Helix Sleep
00:43:21 Protest, Despair & Transmutation; Changing Attachment Hierarchy
00:52:04 Bereavement Support, Medical Risk
01:05:27 Culture, Alcohol & Death; Dying of a Broken Heart, Medical Risk
















