Boston gain of function virus

Please share this video, this research must STOP. Gain of function research in the USA today using enhanced potential pandemic pathogen (ePPP) research

Professor Shmuel Shapira, lead scientist, Israeli Government

https://www.dailymail.co.uk/health/article-11323677/Outrage-Boston-University-CREATES-Covid-strain-80-kill-rate.html

This should be totally forbidden, it's playing with fire

Dr Richard Ebright, Rutgers University, New Brunswick

The research is a clear example of gain of function research.

If we are to avoid a next lab-generated pandemic,

it is imperative that oversight of enhanced potential pandemic pathogen research be strengthened.

it is imperative that officials at US-government agencies,

who repeatedly have placed the public at risk by repeatedly violating the existing policies be held accountable

Prof David Livermore, microbiology, University of East Anglia

given the strong likelihood that the Covid pandemic originated from the escape of a lab-manipulated coronavirus in Wuhan,

these experiments seem profoundly unwise

Boston University's National Emerging Infectious Diseases Laboratories is one of 13 biosafety level 4 labs in the US

Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron

14th October 2022

Boston University School of Medicine

https://www.biorxiv.org/content/10.1101/2022.10.13.512134v1

Predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible,

even in fully vaccinated individuals,

and causes attenuated disease compared with other major viral variants recognized to date

The Omicron spike (S) protein, unusually large number of mutations,

is considered the major driver of these phenotypes

We generated chimeric recombinant SARS-CoV-2

A chimera or chimeric virus

One virus containing genetic material derived from two or more distinct viruses

US Center for Veterinary Biologics

https://www.aphis.usda.gov/animal_health/vet_biologics/publications/notice_05_23.pdf

A new hybrid microorganism,

created by joining nucleic acid fragments from two or more different microorganisms,

in which each of at least two of the fragments,

contain essential genes necessary for replication

We generated chimeric recombinant SARS-CoV-2

Encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate,

and compared this virus with the naturally circulating Omicron variant.