Natural immunity preserves
June 22, 2026
24 min
Full
355 of 364
June 22, 2026
Natural immunity preserves
0:00 / 24:08
Excerpt playback isn’t available for this episode — use the full-episode link.
Search the Record
Moment search isn’t open for this episode yet
When it opens, you’ll be able to type any phrase and jump straight to the second it was said.
Dr John Campbell Episodes Around June 22, 2026
Episode 355 of 364 — walk the feed in the order it was published.
24:08This episodeNatural immunity preserves
Summary
Download free high-res PDFs of the posters, download free copies of my two text books. Any donations using this link help the work of campbell teaching.
https://drjohncampbell.co.uk/
I taught bespoke health care as a fundamental principle for decades.
Does natural and hybrid immunity obviate the need for frequent vaccine boosters against SARS-CoV-2 in the endemic phase?
https://pubmed.ncbi.nlm.nih.gov/36366946/
https://onlinelibrary.wiley.com/doi/10.1111/eci.13906
Stefan Pilz John PA Ioannidis
The coronavirus disease 2019 (COVID-19) pandemic has entered its endemic phase
We observe significantly declining infection fatality rates due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Now
It is crucial but challenging to define current and future vaccine policy,
in a population with a high immunity against SARS-CoV-2,
conferred by previous infections and/or vaccinations.
Vaccine policy must consider the magnitude of the risks conferred by new infection(s),
with current and evolving SARS-CoV-2 variants,
how these risks vary in different groups of individuals,
how to balance these risks against the apparently small, but existent, risks of harms of vaccination,
and the cost-benefit of different options.
More evidence from randomized controlled trials,
and continuously accumulating national health data is required,
to inform shared decision-making with people who consider vaccination options.
Vaccine policy makers should cautiously weight what vaccination schedules are needed,
and refrain from urging frequent vaccine boosters unless supported by sufficient evidence.
The key issue
Whether and how to consider natural immunity after SARS-CoV-2 infections, and hybrid immunity
It is very likely that the large majority of the global population has been infected with SARS-CoV-2,
at least once by late 2022
(Excluding China)
People who have never been infected have probably become a rarity.
It is well established that previous SARS- CoV-2 infections induce a significant and long-lasting protection against reinfections,
and even more so against severe COVID-19.3-6
Lets check the evidence
https://pubmed.ncbi.nlm.nih.gov/35904405/
Risk of reinfection and disease after SARS-CoV-2 primary infection: Meta-analysis
91 studies, n = 15,034,624
Infections n = 158,478 reinfections