The Dark Side of NMN Nobody Tells You About
March 12, 2026
45 min
1
413
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Episode 413 · March 12, 2026
The Dark Side of NMN Nobody Tells You About
0:00 / 45:58
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Pushing the Limits Episodes Around March 12, 2026
Episode 417 of 428 — walk the feed in the order it was published.
1:23:38Holistic Brain Health & Cutting Edge Health Tech with Dr. Elizabeth Harris
45:58This episodeThe Dark Side of NMN Nobody Tells You About
Summary
<p>Is your NAD+ supplement actually working against you?</p> <p>Millions of people are taking NMN or NR thinking they're <br /> doing something smart for their longevity. And the science <br /> behind NAD+ is genuinely extraordinary. But the way most <br /> people are supplementing it is incomplete — and there's <br /> growing evidence it could be creating downstream harm most <br /> people never connect back to their supplement.</p> <p>In this episode I break down the full NAD+ story — the <br /> methylation trap, the CD38 drain, why high-dose NMN may be <br /> elevating your cardiovascular risk markers, and what an <br /> intelligent systems-level approach actually looks like.</p> <p>I co-developed NAD+ Next Gen with Peter Lehrke— and in this episode I walk <br /> you through exactly why every ingredient is in the formula.</p> <p>WHAT WE COVER:<br /> - The 2023 Nature Cardiovascular Research findings on NMN & ADMA<br /> - How high-dose NMN drains your SAM pool and disrupts dopamine, <br /> DNA methylation and homocysteine<br /> - CD38 — the biggest NAD+ drain in ageing nobody talks about<br /> - The bathtub model: precursors, drains, sirtuin efficiency<br /> - Why niacinamide may be smarter than high-dose NMN<br /> - EGCG, resveratrol, apigenin, quercetin, rutin — the why <br /> behind each ingredient<br /> - 6 practical takeaways including which blood test to get now</p> <p>KEY LINKS:<br /> NAD+ Next Gen → https://aevumlabs.co.nz<br /> Rejuvenate Pro → https://shop.lisatamati.com<br /> Pushing The Limits community → https://www.lisatamati.com</p> <p>GET YOUR HOMOCYSTEINE TESTED:<br /> Optimal: below 7–8 µmol/L<br /> Above 10 µmol/L: address your methylation cycle urgently</p> <p>Lisa Tamati is a functional health practitioner, longevity <br /> specialist, co-founder of Aevum Labs, host of Pushing The <br /> Limits, and former elite ultra-endurance athlete with 25 <br /> years and 140+ ultramarathons across the world's most <br /> extreme environments.</p> <p>Visit Lisa's website </p> <p><a href="https://www.lisatamati.com">www.lisatamati.com</a></p> <p>shop.lisatamati.com</p> <p><a href="https://www.longlifehyperbarics.com">www.longlifehyperbarics.com</a></p> <p><a href="https://www.aevumlabs.co.nz">www.aevumlabs.co.nz</a> </p> <p>www.Yourhealthcompass.org</p> <p>www.Myimmuneage.life </p> <p><a href="https://shop.lisatamati.com/collections/health-optimization/products/health-consulting-with-lisa-tamati"> Work with Lisa:</a></p> <p> </p>
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