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Ben Horowitz and Ali Ghodsi: How to Run a $100 Billion Business

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October 15, 2025

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Ben Horowitz founded Loudcloud in the middle of the dot-com bust and sold it for $1.6 billion, then led Andreessen Horowitz from its founding to $46 billion in committed capital. Ali Ghodsi co-founded Databricks, stepped in as CEO during a crisis, and led it to a valuation of over $100 billion.

In this episode of “Boss Talk”, Ben and Ali join a16z General Partners Sarah Wang and Erik Torenberg to share founder war stories, how to hire and make deals, how to keep culture intense without burning employees out, and why founders should raise their ambitions even higher.

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Ben Horowitz and Ali GhodsiBen HorowitzAndreessen HorowitzAli GhodsiBoss Talk BenGeneral Partners Sarah WangErik TorenbergFollow Ali

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Ben Horowitz and Ali Ghodsi: How to Run a $100 Billion Business · A16z · Sentinel