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Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

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November 6, 2025

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Priscilla Chan and Mark Zuckerberg join a16z’s Ben Horowitz, Erik Torenberg, and Vineeta Agarwala to share how the Chan Zuckerberg Initiative is building the computational tools that will accelerate the cure, prevention, and management of all disease by century's end.

They explain why basic science needs $100 million-scale projects that traditional NIH grants can't fund, how their Cell Atlas became biology's missing periodic table with millions of cells catalogued in open-source format, and why their new virtual cell models will let scientists test high-risk hypotheses in silico before investing in expensive wet lab work.

Plus: the organizational shift unifying the Biohub under AI leadership, what happens when biologists and engineers sit side-by-side, and why modern biology labs are expanding compute instead of square footage.

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Guests & Subjects Covered

Mark Zuckerberg & Priscilla ChanPriscilla ChanMark ZuckerbergBen Horowitz Erik TorenbergVineeta AgarwalaChan Zuckerberg InitiativeCell AtlasTimestamps Introduction Building

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