November 28, 2025
9,882
36
0.36%
Every word spoken in this episode is indexed. Type any phrase to jump straight to the moment it was said.
Type any word or phrase that may have been spoken. Click a result to seek the player to that exact moment.
Try a name, a topic, or a quoted line
53:23Now PlayingIn this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platform across models, pricing, and infrastructure, and how it is shifting from a single general-purpose model to a portfolio of specialized systems, custom fine-tuning options, and node-based agent workflows.
They get into why developers tend to stick with a trusted model family, what builds that trust, and why the industry moved past the idea of one model that can do everything. Sherwin also explains the evolution from prompt engineering to context design and how companies use OpenAI’s fine-tuning and RFT APIs to shape model behavior with their own data.
Highlights from the conversation include:
• How OpenAI balances a horizontal API platform with vertical products like ChatGPT
• The evolution from Codex to the Composer model
• Why usage-based pricing works and where outcome-based pricing breaks
• What the Harmonic Labs and Rockset acquisitions added to OpenAI’s agent work
• Why the new agent builder is deterministic, node based, and not free roaming
Timestamps:
Stay Updated:
If you enjoyed this episode, be sure to like, subscribe, and share with your friends!
Find a16z on X[]()
Find a16z on LinkedIn[]()
Listen to the a16z Podcast on Spotify[]()
Listen to the a16z Podcast on Apple Podcasts[]()
Follow our host[]()
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details, please see [a16z.com/disclosures]().
Sentinel Indexing in Progress
Metadata and chapters are available. Claim extraction for this episode is pending.
All video content is delivered via YouTube embedded players in accordance with the YouTube Terms of Service. Sentinel provides research tools that promote discovery and accountability across political media.