WATCH: Biden lays out “moonshot” effort to reduce cancer deaths by 50% | 2023 State of the Union

In his State of the Union speech Tuesday night, President Joe Biden outlined his “cancer moonshot,” an ambitious plan that he first started when he vice president to former President Barack Obama.

“Our goal is to cut the cancer death rates at least by 50 percent in the next 25 years, turn more cancers from death sentences to treatable diseases [and] provide more support for patients and their families,” Biden said.

Biden nodded to former President George W. Bush’s bipartisan effort to “transform the global fight against HIV,” adding that he believes a similarly successful push can help in the fight against cancer.

Biden’s Feb. 7 address comes a year after Russia invaded Ukraine and amid new diplomatic tensions between the U.S. and China over a suspected surveillance balloon. This is Biden’s second State of the Union address, as his first was a joint address to Congress in April 2021.

Last year, Biden used his address to emphasize themes of bipartisanship and unity. But he now faces a split Congress, with the GOP-led House launching efforts to investigate his family and his administration.

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