How to Optimize Cognitive Function & Brain Health | Dr. Mark D'Esposito
February 19, 2024
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2:32:38Now PlayingHow to Optimize Cognitive Function & Brain Health | Dr. Mark D'Esposito
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as posted by the channelIn this episode, my guest is Dr. Mark D'Esposito, M.D., a neurologist and professor of neuroscience and psychology at the University of California, Berkeley. We discuss the brain mechanisms underlying cognition and the forms of memory required for focus, productivity, planning and achieving goals, and learning. We discuss neurochemicals such as dopamine and acetylcholine and how they can be leveraged to improve cognitive functioning. We also discuss concussion, traumatic brain injury (TBI), Alzheimer's, and Parkinson's disease, and ways to restore or slow cognitive decline by using pharmacologic, lifestyle and behavioral protocols. This episode provides a modern understanding of cognition and memory and actionable tools to optimize brain health and function.
*Thank you to our sponsors*
Eight Sleep
*Dr. Mark D'Esposito*
Academic profile
Lab website
BrainHealth project
Publications
*Journal Articles*
Cognitive and attentional mechanisms in delay of gratification
InvertedUShaped Dopamine Actions on Human Working Memory and Cognitive Control
Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey
Clinical experience with the α2Aadrenoceptor agonist, guanfacine, and Nacetylcysteine for the treatment of cognitive deficits in “LongCOVID19”
Estrogen Shapes DopamineDependent Cognitive ProcessesImplications for Women's Health
Ongoing dynamics in largescale functional connectivity predict perception
*Other Resources*
The BrainHealth Project
Neuroscouting
*Huberman Lab Episodes Mentioned*
Nicotine's Effects on the Brain & Body & How to Quit Smoking or Vaping
Tools to Enhance Working Memory & Attention
Dr. Matthew WalkerThe Science & Practice of Perfecting Your Sleep
How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks
*People Mentioned*
Brian LevineProfessor Dept. of Psychology, University of Toronto
Matthew WalkerProfessor of Neuroscience & Psychology, UC Berkeley
Michael MerzenichProfessor Emeritus Neuroscience, USCF
David Hubel and Torsten WieselNobel Prize (1981)
Emily JacobsAssociate Professor of Psychology, UC Santa Barbara
Art KramerProfessor Emeritus, University of Illinois UrbanaChampaign
Eddie ChangProfessor of Neurological Surgery, UCSF
Karl DeisserothProfessor and Psychiatrist, Stanford
Sepideh SadaghianiAssociate Professor of Psychology, University of Illinois UrbanaChampaign
*Timestamps*
#HubermanLab
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