Big Think
Big Think
@bigthink·8.8M subscribers·10.1K videos

The 5 core principles of life | Nobel Prize-winner Paul Nurse

Posted

May 19, 2023

Views

2,495,168

Likes

62,633

Comments

2,943

Engagement

2.63%

Search the Record

Indexed

Every word spoken in this episode is indexed. Type any phrase to jump straight to the moment it was said.

Type any word or phrase that may have been spoken. Click a result to seek the player to that exact moment.

Try a name, a topic, or a quoted line

Chapters

YouTube Description

as posted by the channel

Become a Big Think member to unlock expert classes, premium print issues, exclusive events and moreNobel Prizewinning scientist Paul Nurse defines the 5 core principles of life.

Subscribe to Big Think on YouTube ►

Up next, You can slow down aging with zero weird tricks ►

What is the essence of being alive? This is the question that geneticist and cell biologist Paul Nurse dissects in his book What Is Life? At the core of life is the cell — an entity that can grow, divide, and reproduce.

Using yeast as a model organism, Nurse discovered a similarity in cell reproduction mechanisms between yeast and humans, hinting at a shared ancestral origin for all life. This commonality extends to genes, the units of inheritance, first recognized in pea plants by Gregor Mendel. Charles Darwin's theory of evolution by natural selection proposes that life adapts and evolves, favoring traits — and the genes that encode them — that are advantageous for survival.

The essence of life, therefore, is a complex orchestration of chemistry and information management that allows organisms to adapt and persist through inheritance.

----------------------------------------------------------------------------------

About Paul Nurse:

Paul Nurse, Ph.D, is a British biochemist. He was awarded the 2001 Nobel Prize in Physiology or Medicine with Leland H. Hartwell and R. Timothy Hunt for their discoveries regarding cell cycle regulation by cyclin and cyclin dependent kinases. He became Rockefeller University's ninth president in 2003.

----------------------------------------------------------------------------------

Read more of our stories biology:

Biology’s unsolved chicken-or-egg problem: Where did life come from?

What does it look like to “turn on” a gene?

“Spooky” quantum biology might cause your DNA to mutate

----------------------------------------------------------------------------------

About Big Think | Smarter Faster™

► Big Think

Our mission is to make you smarter, faster. Watch interviews with the world’s biggest thinkers on science, philosophy, business, and more.

► Big Think+

Looking to ignite a learning culture at your company? Prepare your workforce for the future with educational courses from the world’s biggest thinkers. Trusted by Ford, Marriot, Bank of America, and many more. Learn how Big Think+ can empower your people today

----------------------------------------------------------------------------------

Want more Big Think?

► Daily editorial features

► Get the best of Big Think right to your inbox

► Instagram

Guests & Subjects Covered

Nobel Prize-winningPaul NurseWhat Is Life AtGregor Mendel Charles Darwin'sThe CellThe GeneInformation WhatNobel Prize

Sentinel Indexing in Progress

Metadata and chapters are available. Claim extraction for this episode is pending.

All video content is delivered via YouTube embedded players in accordance with the YouTube Terms of Service. Sentinel provides research tools that promote discovery and accountability across political media.

The 5 core principles of life | Nobel Prize-winner Paul Nurse · Big Think · Sentinel