Big Think
Big Think
@bigthink·8.8M subscribers·10.1K videos

The science of delivering cures straight to your cells | Eric Kelsic

Posted

December 1, 2025

Views

30,566

Likes

1,106

Comments

60

Engagement

3.81%

Search the Record

Indexed

Every word spoken in this episode is indexed. Type any phrase to jump straight to the moment it was said.

Type any word or phrase that may have been spoken. Click a result to seek the player to that exact moment.

Try a name, a topic, or a quoted line

Chapters

YouTube Description

as posted by the channel

Become a Big Think member to unlock expert classes, premium print issues, exclusive events and more

“Until very recently, I thought I would die with the same genome that I was born with.”

Subscribe to Big Think on YouTube ►

Up next, Why 2025 is the single most pivotal year in our lifetime | Peter Leyden ►

What if the genome you were born with wasn’t fixed? Eric Kelsic, CEO of Dyno Therapeutics, explains how gene therapy is moving from promise to reality, delivering treatments directly to cells and potentially curing diseases for a lifetime.

Read the video transcript ►

© Freethink Media Inc., All Rights Reserved.

----------------------------------------------------------------------------------

Go Deeper with Big Think:

►Become a Big Think Youtube Member

Get exclusive classes and early, adfree access to new releases without leaving Youtube.

►Become a Big Think Web Member

Get the entire Big Think Class library, premium print issues, live events, and more.

►Subscribe to Big Think on Substack

Get all of your favorite Big Think content delivered to your inbox.

----------------------------------------------------------------------------------

About Eric Kelsic, PhD

Prior to founding Dyno, Eric led a team to develop the technology underlying Dyno’s artificial intelligence powered capsid engineering platform in George Church’s lab at the Wyss Institute of Harvard Medical School. There he measured the first comprehensive fitness landscape of the adeno-associated virus (AAV) capsid protein and co-discovered the AAV MAAP gene. He earned a PhD in Systems Biology from Harvard University and a BS in Physics from Caltech. Under Eric’s leadership Dyno has raised over $100M in VC financing, including a 2021 Series A led by a16z and signed partnership with world-leading gene therapy companies (Novartis, Sarepta, Roche, Spark and Astellas). Dyno was named Xconomy’s 2020 Startup of the Year and Eric was recognized as one of Endpoint’s 20 under 40 next-gen biotech leaders in 2021.

Guests & Subjects Covered

Peter LeydenEric Kelsic CEODyno TherapeuticsMeet Eric Kelsic MakingZolgensma ImprovingGo DeeperBig Think BecomeYoutube Become

Sentinel Indexing in Progress

Metadata and chapters are available. Claim extraction for this episode is pending.

All video content is delivered via YouTube embedded players in accordance with the YouTube Terms of Service. Sentinel provides research tools that promote discovery and accountability across political media.

The science of delivering cures straight to your cells | Eric Kelsic · Big Think · Sentinel