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How evolution works, in 54 minutes | Sean B. Carroll: Full Interview

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December 19, 2025

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How does life build complexity from pure chance? Sean B. Carroll takes up the “staircase of evolution,” showing how random mutation and natural selection shape everything from the smallest cells in our bodies to entire species.

If you want to understand the forces that silently govern life, this discussion reframes evolution as an active, ongoing process shaping every organism, including you.

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About Sean B. Carroll:

Sean B. Carroll is an award-winning scientist, author, educator, and film producer. He is Distinguished University Professor and the Andrew and Mary Balo and NIcholas and Susan Simon Chair of Biology at the University of Maryland, and an Investigator of the Howard Hughes Medical Institute. He was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin.

An internationally-recognized evolutionary biologist, Carroll's laboratory research has centered on the genes that control animal body patterns and play major roles in the evolution of animal diversity. In recognition of his scientific contributions, Carroll has received the Benjamin Franklin Medal in Life Sciences, been elected to the National Academy of Sciences and the American Philosophical Society, named a Fellow of the American Academy of Arts and Sciences and the American Association for the Advancement of Science, and elected an Associate Member of the European Molecular Biology Organization.

His latest book is A Series of Fortunate Events.

Guests & Subjects Covered

Sean B CarrollSpeciation TheHypermutation ImmunologicalDNA HowAlfred Russel Wallace TheoryArchaeopteryx WallaceThe Darwin-Wallace Theory ReadGo Deeper

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