March 6, 2021
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2:53Now PlayingAn Italian research lab has come up with an antibody treatment for Covid-19 that its developers say will be 80 times more potent than the one given to former U.S. President Donald Trump in his most critical days in hospital last year.
The therapy is derived from the blood of people who’ve recovered from Covid, and relies on 453 different antibodies. It will also be administered as a single shot rather than a drawn-out infusion, which has been the norm for similar drugs. Clinical trials of about 3,000 doses produced so far started in Italy Thursday, and a roll out for general use could be approved as early as this summer.
“The focus of our work has been on dosage,” said Fabrizio Landi, president of the Toscana Life Sciences Foundation, the promoter of the project. “When Trump received an antibodies drug he had to have an hours-long infusion. We are aiming at getting to a dose 80 times more powerful than the one he got.”
As the world struggles to deal with the deadliest pandemic in recent history -- one that has left more than 2.5 million people dead -- vaccines and treatments have become critical.
Italy, where the pandemic has killed almost 99,000 people, has turned to a well-tested pharmaceutical hub for answers. Created more than a century ago as a research center by Achille Sclavo, a pioneer in vaccines, the area around Siena is where an antidote for anthrax was found, where GlaxoSmithKline Plc produces its meningitis shots and dozens of startups funded by Toscana Life Sciences Foundation work on vaccines.
The country’s Covid antibody-treatment project backed by Toscana is being funded by the Monte Paschi di Siena SpA foundation, the Tuscany region, the Italian government and the European Union.
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