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Critical shortage: US used nearly half its key missiles in Iran war

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April 21, 2026

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The US military has significantly depleted its stockpile of key missiles during the war with Iran and created a “near-term risk” of running out of ammunition in a future conflict should one arise in the next few years, according to experts and three people familiar with recent internal Defense Department stockpile assessments.

Over the last seven weeks of war, the US military has expended at least 45% of its stockpile of Precision Strike Missiles; at least half of its inventory of THAAD missiles, which are designed to intercept ballistic missiles; and nearly 50% of its stockpile of Patriot air defense interceptor missiles, according to a new analysis conducted by the Center for Strategic and International Studies.

CNN national security correspondent Natasha Bertrand has the story, and retired US Army Major Harrison Mann weighs in on the implications of the missile stockpile depletion.

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Critical shortageThe USDefense DepartmentPrecision Strike MissilesInternational Studies CNNNatasha BertrandRetired US ArmyDoes US

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Critical shortage: US used nearly half its key missiles in Iran war · CNN · Sentinel