Dr John Campbell
Dr John Campbell
@campbellteaching·3.3M subscribers·3.1K videos

Basic Reproduction Number, R0

Posted

March 22, 2020

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Basic reproduction number R0

R0 tells you the average number of people who will catch a disease from one contagious person.

Spread into a population with no previous exposure to the antigen

Assumes no pre-existing immunity through exposure or vaccination

R0 = 1

R0 greater than 1

R0 less than 1

Determining factors of R0

Infectious period

How long an infection is contagious for

Flu, typically up to 8 days

Flu in children, up to two weeks

Longer an infection is contagious for, the higher the R0

Contact rate

How many people an infected person comes into contact with

E.g. R0 will be lower if a person stays at home, higher if they are out and about

Mode of transmission

Shedding pottential

Rapid speed if airborne, flu or measles. No physical contact or fomite necessary

Slower if transmitted by body fluids, e.g. Ebola, Hepatitis B, C, or HIV,

Influenza Droplet R0 = 0.9 – 2.1

2009 Droplet R0 = 1.4 – 1.6

Hepatitis C Body fluids R0 = 2

Ebola Body fluids R0 = 2

1918 Droplet R0 = 1.4 – 2.8

HIV Body fluids R0 = 4

Smallpox Droplet R0 = 3.5 - 6

Mumps Droplet R0 = 4-7

Pertussis Droplet R0 = 5.5

Measles Airborne R0 = 18

Super-spreaders

20/80 rule

20% of infected individuals are responsible for 80% of transmissions

Individual reproductive number

Guests & Subjects Covered

R RR InfectiousR ContactEg REbola Hepatitis B CHIV Influenza Droplet RDroplet RHepatitis C Body

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Basic Reproduction Number, R0 · Dr John Campbell · Sentinel