Dr John Campbell
Dr John Campbell
@campbellteaching·3.3M subscribers·3.1K videos

Comparative immunity update

Posted

October 19, 2021

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High infection rates in UK, going down in US

Lower functional immunity in our population than most other

Western European countries

Early vaccine roll out

AstraZeneca protects slightly less well than Pfizer against infection and transmission, particularly delta variant

Slightly lower overall vaccination coverage, particularly vaccinating teenagers

Fewer social restrictions

High rates of testing

UK, ONS

Two vaccine doses give similar protection as previous infection

Two doses of either Pfizer-BioNTech or Oxford-AstraZeneca

Provided a similar level of protection as having had a previous natural infection of coronavirus

During delta variant times

Vaccination reduced the risk of testing positive,

both when the alpha variant was dominant in the UK (1 December 2020 to 16 May 2021)

and when the delta variant was dominant (17 May to 14 August 2021)

Two doses of Pfizer-BioNTech

Reduced the risk of testing positive by 73% in the delta period

Two doses of Oxford-AstraZeneca

Reduced the risk of testing positive by 62% in the delta period

Two vaccination doses, more effective than one at preventing symptomatic infection in both periods.

Three weeks after vaccination

Two doses always more protective than one

(75% v 58%)

Inconsistent with covid symptom study

Two doses of the Pfizer

87% protection against infection

Two doses of the AstraZeneca

71% protection against infection

Natural infection alone

Only gave 65% protection against catching it again

Israeli data consistent with ONS but inconsistent with covid symptom study

Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel

Vaccination was highly effective

Estimated efficacy for documented infection of 92·8%

Hospitalization 94·2%

Severe illness 94·4%

Death 93·7%

Protection from prior SARS-CoV-2 infection

Estimated efficacy for documented infection of 94·8%

Hospitalization 94·1%

Severe illness 96·4%

All deaths registered in the week to 8 October

COVID-19 deaths fall in England, Northern Ireland and Scotland

Up in Wales

Total UK deaths in the week, 12,490

14.7% above the average in 2015 to 2019

820 involved the coronavirus (COVID-19)

154 fewer than the previous week

Deaths involving COVID-19, 1 in 15 deaths (6.6%).

UK total deaths include non-residents.

1 million people in UK countries had COVID-19 in the latest week

1.63% in England (1 in 60 people)

One in 70 people the week before

2.18% in Wales (1 in 45 people)

One in 55 people the week before

0.82% in Northern Ireland (1 in 120 people)

One in 130 people the week before

1.26% in Scotland (1 in 80 people)

One in 60 people the week before

Greg and Peter

Hello John, Just to let you know that one of my posts referring to your video on aspiration has been pulled from LinkedIn. This is the first time that one of my posts has been pulled and I have put out some pretty controversial posts on other subjects.

Feedback from vaccine manufacturers

Guests & Subjects Covered

US LowerWestern EuropeanUK ONS TwoOxford-AstraZeneca ProvidedPfizer-BioNTech ReducedOxford-AstraZeneca ReducedIsrael VaccinationOctober COVID-

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Comparative immunity update · Dr John Campbell · Sentinel