Dr John Campbell
@campbellteaching·3.3M subscribers·3.1K videos
Ivermectin in Japan
Posted
November 23, 2021
Views
1,539,253
Likes
49,614
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Engagement
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November 23, 2021
1,539,253
49,614
12,176
4.01%
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Antivirals in Japan
Ivermectin allowed as a treatment on August 13
Doctors can prescribe without restrictions
People can buy it legally from India
Dr. Haruo Ozaki, Chairman of the Tokyo Medical Association
The situation is that the whole country is suffering from disasters.
No one will listen to me, so I will come up with a new policy
The antiparasitic drug "ivermectin" shows the number of infections and deaths of the new corona in a country that is prophylactically administered for another disease in Africa.
It is necessary to thoroughly study the clinical trial, but it seems that we are at the stage where it is okay to have the patient give an informed outlet and get permission to use it
Japan
Population, 126 million
Cases, + 79
Deaths, + 2
Lowest since June 23, 2020
Currently reopening
More than 76% of population is fully vaccinated
(South Korea, high vaccination but uptick in infections)
Boosters to start in December
Ingrained pre-pandemic flu seasons mask wearing
Delta variant wave ends
Delta variant “self-extinction”
Viral genetic mutations
Ituro Inoue, professor, National Institute of Genetics
Delta variant in Japan accumulated too many mutations
Virus’s error-correcting protein, nsp14
Majority of nsp14 specimens in Japan seemed to have undergone many genetic changes in mutation sites called A394V
Non-structural protein, made by the virus
Therefore errors accumulated leading to non-viability
Also
More people in Asia have a defense enzyme called APOBEC3A that attacks RNA viruses,
Including the SARS-CoV-2 virus that causes COVID-19,
when compared to people in Europe and Africa.
National Institute of Genetics and Niigata University
Research to discover how the APOBEC3A protein affects the nsp14 protein
A394V discovered in 24 other countries
SARS ended abruptly in 2003
Working on a drug to inhibit nsp14
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