Omicron, should I expose myself?
January 22, 2022
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Dr John Campbell Episodes Around January 22, 2022
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29:11Now PlayingOmicron, should I expose myself?
YouTube Description
as posted by the channelLink to free download of my 2 textbooks
Physiology book in hard copy
Pathophysiology book in hard copy
US variants data
US omicron history
November 29
Index patient, 48 year old unvaccinated man, Nigeria
Nebraska, 6 people diagnosed by PCR and genomic sequencing
Onset was 73 hours (range = 33–75 hours)
Incubation period
Original version, five days
The Delta variant, four days
Omicron, 2 to 3 days
Viral Load
Alpha and Delta variants
Peak viral load 3 days after infection
Clear the virus about six days after that
Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron
Omicron and Delta produced similar levels of infectious virus
Infections a day shorter with omicron compared to delta
Omicron infects upper airways as opposed to lungs
Omicron antibodies neutralise delta virus
Offshoot of Omicron variant, England
BA.2 may be even more contagious than original omicron
UK Health Security Agency
Designating BA.2 a variant under investigation
increasing numbers of BA.2 sequences identified both domestically and internationally
May have an increased growth rate over BA.1
Vaccine effectiveness with omicron
After a 2-dose primary course of vaccination
Vaccine protection against mild disease has largely disappeared by 20 weeks after vaccination
After a booster dose
Protection initially increases to around 65 to 70%
but drops to 45 to 50% from 10+ weeks
Therefore
It is therefore likely that current vaccines offer limited long-term protection against infection or transmission.
Protection against severe disease
Vaccine effectiveness against hospitalisation is estimated at 92%
and remains high at 83% 10+ weeks after the booster dose
John’s booster
20th November
So my protection against hospitalisation goes down from 92% to 83% by soon
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