Is new omicron more severe?
February 25, 2022
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Dr John Campbell Episodes Around February 25, 2022
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9:00Now PlayingIs new omicron more severe?
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as posted by the channelFrom Danish data, no, but more younger people are admitted to hospital
Risk assessment of Omicron BA.2
The Omicron SARS-CoV-2 variant has quickly become dominant in many countries,
significantly higher growth potential than the Delta variant
Omicron variant is more transmissible than the Delta variant
Secondary Attack Rate
BA.1 29%
BA.2 39%
and it has shown reduced sensitivity to neutralizing antibodies.
Vaccine induced protection against infection is also clearly reduced for the Omicron compared to the Delta variant.
Transmissibility is lower in fully vaccinated individuals and even lower in booster vaccinated individuals, compared to unvaccinated
Preliminary analyses
a 36%-80% risk reduction in hospitalization for the Omicron compared with the Delta
with most studies reporting a risk reduction between 45%-68%.
Omicron
Lineages B.1.1.529, BA.1, BA.2 and BA.3. BA.1
accounts for 97% of omicron worldwide
Denmark
Week 52, 2021, 20%
Week 3, 2022, 66%
an increase in the proportion of BA.2 and a decrease in the proportion of BA.1
BA.2 is probably beginning to take over in India, Philippines, European countries
Qatar, BA.2 seems to be dominant
Increased growth potential
Higher transmissibility and/or
increased ability to evade the immune system compared to BA.1.
Current knowledge about severity
no difference in hospital admission risk was detected for BA.1 and BA.2
(n = 932 patients)
BA,1 median age of hospital admission, 51
BA,2 median age of hospital admission, 40
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