Plausable mechanism for infertiliy after vaccines

Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic

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Observed

Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics

Limited data, relationship, COVID-19 vaccination status and birth rates.

Objectives

Nationwide data from the Czech Republic

Rates of successful conceptions (SCs)

(conceptions leading to live births 9 months later)

For women who were either vaccinated or unvaccinated against COVID-19 before SC.

Summary monthly COVID-19 vaccination and birth data

Women in the Czech Republic aged 18–39

January 2021 to December 2023.

Results

1,300,000 women aged 18–39 years in the Czech Republic

Proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021.

At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated,

compared to those that were unvaccinated, before SC.

SC rates for the vaccinated group were much lower than expected based on their proportion of the total population.

Conclusions

SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated.

These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility.