Combining ADHD Medications
December 8, 2024
5,346
179
76
4.77%
Search the Record
IndexedEvery word spoken in this episode is indexed. Type any phrase to jump straight to the moment it was said.
Type any word or phrase that may have been spoken. Click a result to seek the player to that exact moment.
Try a name, a topic, or a quoted line
Dr John Kruse Episodes Around December 8, 2024
See what was published immediately before and after this episode.
23:52Now PlayingCombining ADHD Medications
Chapters
YouTube Description
as posted by the channelMain Chapters:
The medications that the FDA has sanctioned for treating ADHD have all been approved as stand-alone agents only. But we know that combination medication therapy is widespread in the treatment of ADHD. Aren't stimulants powerful and dangerous enough alone? Why add on something else?
Despite the powerful ability of stimulants to reduce ADHD symptoms, for many, residual symptoms persist. Others can't tolerate stimulates, or have side effects (like insomnia) worsened by the drugs. Co-morbid conditions like depression, PTSD, anxiety, and OCD are common with ADHD, which also often prompts the use of combination therapy.
Most of the research on combination therapy for ADHD is descriptive - how often does it occur, with which medications, and for what subpopulations. But some experimental research indicates that two combinations: atomoxetine + stimulants and guanfacine + stimulants can lead to improved outcomes and does not increase the risk of serious side effects.
When combining medications, one should have clear treatment goals in mind, monitor responses closely, and start low, particularly with agents that may have overlapping modes of action.
-----
Follow on Medium for hundreds of full length articles on this subject and more!
Access to full articles requires paid membership.
-----
References:
Combined Stimulant and Guanfacine Administration in Attention-Deficit/Hyperactivity Disorder: A Controlled, Comparative Study (2016)
)302192/fulltext
A Systematic Review of Combination Therapy with Stimulants and Atomoxetine for Attention-Deficit/Hyperactivity Disorder, Including Patient Characteristics, Treatment Strategies, Effectiveness, and Tolerability (2013)
A retrospective claims analysis of combination therapy in the treatment of adult attention-deficit/hyperactivity disorder (ADHD) (2009)
Combination pharmacotherapy for adult ADHD (2006)
Natural Product-Derived Treatments for Attention-Deficit/Hyperactivity Disorder: Safety, Efficacy, and Therapeutic Potential of Combination Therapy (2016)
Full Chapter list:
-------------------------
Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions.
Subscribe if you're curious about how neuroatypical brains can optimize their functioning in our shared, and somewhat strange, world.
ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of Politics related videos have an orange background.
Dr. Kruse has posted videos in the "Videos", "Live", and "Shorts", sections of this channel.
You're welcome to email him with topics you want discussed or people you think he should interview.
drjohnkruse@gmail.com
#health #mentalhealth #adhd #medication
Guests & Subjects Covered
Sentinel Indexing in Progress
Metadata and chapters are available. Claim extraction for this episode is pending.
All video content is delivered via YouTube embedded players in accordance with the YouTube Terms of Service. Sentinel provides research tools that promote discovery and accountability across political media.