Dr John Kruse
Dr John Kruse
@drjohnkruse·16.8K subscribers·467 videos

Weekly Q&A: Agomelatine for ADHD

Posted

May 6, 2026

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Join me for my Weekly Mental Health Recap and Q&A!

Livestream every Tuesday at 9:00am West Coast USA / 12:00pm East Coast USA / 6:00am Hawaii / 6:00pm Central European

Video released this week:

- Agomelatine for ADHD

After a 1 minute recap of the video, I’ll be available for questions on this topic or any other related to Mental Health.

- Agomelatine for ADHD:

Agomelatine is an antidepressant available in Europe and Australia, but not the US, despite evidence that it is as effective as other antidepressants, with lower likelihood of side effects. While it can cause an elevation in liver enzymes, potential serious liver problems are generally prevented by routine blood testing. Agomelatine activates the two melatonin receptors involved in propagating circadian signals throughout the body and brain; it also has serotonin 2C blocking properties. A small amount of research indicates that individuals with ADHD may show symptom reduction while taking agomelatine.

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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions.

Subscribe if you're curious about how neuroatypical brains can optimize their functioning in our shared, and somewhat strange, world.

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Weekly Q&AWeekly Mental Health RecapQA LivestreamWest Coast USAEast Coast USACentral European VideoADHD AfterMental Health

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Weekly Q&A: Agomelatine for ADHD · Dr John Kruse · Sentinel