Lost Debate
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The New Science of Psychedelics

Posted

June 21, 2026

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What if psychedelics could be engineered to create specific emotions, experiences, or even states of consciousness on demand?

In this conversation, Ravi Gupta speaks with Atlantic staff writer Ross Andersen about the rapidly evolving science of psychedelics. They discuss everything from mysterious mushrooms that reliably produce the same hallucinations to AI-powered efforts to design entirely new psychedelic compounds. Along the way, they explore the therapeutic promise of these drugs, the risks of over-engineering consciousness, and whether the unpredictability of psychedelic experiences is actually what makes them valuable.

Topics include:

- The next generation of psychedelic medicine

- AI-designed drugs and altered states

- Psilocybin, MDMA, and ibogaine research

- Can scientists engineer joy, clarity, or awe?

- Why some researchers worry we're removing the point of the psychedelic experience

#Psychedelics #Psilocybin #MentalHealth #AI #Neuroscience #HowToChangeYourMind #Consciousness #Science

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Guests & Subjects Covered

Ravi GuptaRoss AndersenPsilocybin MDMALostDebate Notes

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The New Science of Psychedelics · Lost Debate · Sentinel