November 9, 2018
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1:22:21Now PlayingMIT Computational Biology: Genomes, Networks, Evolution, Health
Prof. Manolis Kellis
Fall 2018
Lecture 17 - Whole-genome comparative genomics: Genome Assembly, Genome Alignment, Genome Duplication
1. Genome assembly
- Consenus-layout-overlap methods
- String graph methods
2. Whole-genome alignment
- Resolving region correspondence
- Gene-based global genome alignment
- Mechanisms of genome evolution
3. Whole genome duplication
- Evolutionary signature of WGD
- Emergence of new functions
Lecture 18 Slides:
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