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Open Source, Agents, and Specialization: What's Next in AI?

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December 8, 2025

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The biggest opportunity in AI today is using open-source models to build specialized tools that solve real problems.

Konstantine Buhler, Partner at Sequoia Capital, and Kari Briski, Vice President of Generative AI software at NVIDIA, discuss:

- Moving from “one big model” thinking to specialized agents, open-source foundations, and human-in-the-loop workflows.

- What the most productive workers will be doing in five years (hint: it's not coding).

- Why memory, communication, and security are the three big unlocks for agents.

See how teams are already turning open models into domainspecific AI agents that boost accuracy, speed, and ROI

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Open Source, Agents, and SpecializationKonstantine Buhler PartnerSequoia CapitalKari Briski Vice PresidentGenerative AI

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Open Source, Agents, and Specialization: What's Next in AI? · Nvidia · Sentinel