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Here's how one experimental flu shot aims to target 20 viruses | JUST THE FAQS

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November 28, 2022

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Researchers say their experimental flu vaccine could target 20 viruses with one shot. What makes this vaccine different than the annual flu shot?

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Annual influenza vaccines protect against four strains of flu, but because the strains circulating in people can change so much, we typically need an entirely new vaccine each year to help prevent serious illness.

Plus, with 20 possible types of flu virus, vaccines that protect against four strains likely offer little protection against a pandemic caused by one of the other 16 influenza types. Flu that circulates in birds, pigs and other animals has the potential to jump into people.

Most previous universal flu vaccine efforts have tried targeting parts of the influenza virus that are present across many strains. Unfortunately, these targets have been hard to reach or didn't provide the hoped-for effectiveness. By taking aim at all 20 different types of influenza simultaneously, the scientists behind the new vaccine hope to provide at least some protection against all of the possible lineages. "We decided to throw the whole kitchen sink into this vaccine," said Scott Hensley, who led the research, published Thursday in the journal Science.

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Here's how one experimental flu shot aims to target 20 viruses | JUST THE FAQS · USA Today · Sentinel