The Effects of Cannabis (Marijuana) on the Brain & Body
In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more.
October 3, 2022
2 hr 38 min
92
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Episode 92 · October 3, 2022
The Effects of Cannabis (Marijuana) on the Brain & Body
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The Effects of Cannabis (Marijuana) on the Brain & Body
Summary
In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.
For the full show notes, visit hubermanlab.com.
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Timestamps
(00:00:00) Cannabis (Marijuana)
(00:005:02) Sponsor: LMNT
(00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety
(00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD
(00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects
(00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains
(00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)
(00:35:18) Sponsor: AG1
(00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence
(00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function
(00:53:07) Biological Effects of Cannabis
(00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia
(01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage
(01:09:41) Brain Areas Affected by THC & CBD, Side Effects
(01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine
(01:26:41) Does Cannabis Increase Creativity?
(01:35:08) Chronic Cannabis Use & Changes in Speech Patterns
(01:46:46) Cannabis & Libido, Dopamine & Prolactin
(01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility
(02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences