Human Guinea Pigs About to Embark on World's First 20-Hour Qantas Flight

For decades, travelers have stoically endured jet lag as an unavoidable menace on long journeys. Now, as airlines push for record-breaking non-stop flights halfway around the planet, efforts to counter the debilitating symptoms are turning into a billion-dollar industry.

Fresh insight into the physical and emotional toll of ultra-long-haul travel should emerge this weekend when Qantas Airways Ltd. flies direct from New York to Sydney. No airline has ever completed that route without stopping. At nearly 20 hours, it’s set to be the world’s longest flight, leaving the U.S. on Friday and landing in Australia during its Sunday morning.

This will be more than an endurance exercise. Scientists and medical researchers in the cabin will turn Qantas’s brand-new Boeing Co. Dreamliner into a high-altitude laboratory. They’ll screen the brains of the pilots for alertness, while monitoring the food, sleep and activity of the few dozen passengers — including yours truly. The aim is to see how humans hold up to the ordeal.

The proliferation of super-long flights — Singapore Airlines Ltd. resumed non-stop services to New York last year — is partly driven by the development of lighter, more aerodynamic aircraft that can fly further.

As part of research aimed at reducing jet lag, passengers on board will effectively switch to Sydney time as soon as they leave New York late Friday. Rather than following the standard practice of serving food and dimming the lights after takeoff, Qantas plans to keep everyone awake for six hours. They’ll be helped by food containing hot peppers and spices.

“The passenger research will test alternatives to how airlines have managed in-flight service for decades,” Qantas Chief Executive Officer Alan Joyce said. The industry’s traditional schedule may not be the best way to switch the body clock to the destination’s time zone, he said.

The physical burden on customers is putting a renewed focus on jet lag, and creating a supermarket of products and home-made creations to ease the suffering. In that shopping basket: melatonin tablets, Pfizer Inc.’s anti-anxiety medication Xanax, and Propeaq light-emitting glasses that claim to get the body back on track. And yes, there’s an app for that and many other potential remedies.

The potential customer base is staggering. The International Air Transport Association expects some 4.6 billion people to take a flight in 2019, a total that will jump to 8.2 billion in 2037.

Demand for jet-lag therapies is growing at about 6% each year and the industry will be worth $732 million in 2023, according to BIS Healthcare. The broader sleeping-disorder market — dominated by pills — is worth $1.5 billion and will swell to $1.7 billion by 2023, GlobalData says, adding that more than 80 drugs targeting disturbed sleep are in clinical development.

Jet lag typically strikes when a traveler crosses three times zones or more in quick order, leaving the body’s internal clock running to the timetable at home. The chief complaint after touching down is often overwhelming fatigue during the day or merciless insomnia at night. The fallout can be worse heading east, because traveling in that direction effectively reverses the normal day-and-night cycle.

Unsettling as they are, those ailments barely do jet lag justice.

Each of the billions of cells in the human body has its own clock, and vital processes including heart function, food absorption and metabolism are all disrupted when organs get out of step, said Carrie Partch, a biochemist and associate professor at the University of California Santa Cruz who has studied the circadian rhythm for 20 years.

“Jet lag is more than just an inconvenience,” Partch said in an interview. “It’s pretty devastating physiologically. If you’re a constant traveler, you’ll probably put on more weight, you’ll probably have cardiovascular challenges and you may have some behavioral changes.”

While researchers in this field understand how light enters the brain and adjusts the master clock, they’re still learning more. As recently as 2017, scientists won a Nobel prize for discovering molecular mechanisms that control circadian rhythms. Even if the core proteins of a rodent can be manipulated in a laboratory to speed up internal clock adjustment, a fast-acting pill that can do the same for frequent flyers is a way off, Partch said.

Subscribe to our YouTube channel

TICTOC ON SOCIAL:

Follow TicToc on Twitter

Like TicToc on Facebook

Follow TicToc on Instagram

Subscribe to our newsletter

TicToc by Bloomberg is global news for the life you lead. We are a 24/7 news network that covers breaking news, politics, technology, business and entertainment stories from around the globe, supported by a network of Bloomberg’s 2,700 journalists across 120 countries.