Delta, double hospital risk

NZ, Australia and Hospital admission and emergency care attendance risk for SARSCoV2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concerna cohort study

Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study

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Public Health England (PHE) and Medical Research Council

SARS-CoV-2 delta (B.1.617.2) first detected in England in March, 2021

Suspected to cause more severe disease than alpha (B.1.1.7)

Determining the relative risk of hospital attendance

England between March 29 and May 23, 2021

All infected with alpha or delta

Public Health England’s Second-Generation Surveillance System

COVID-19-associated deaths dataset

National Immunisation Management System

NHS Digital Secondary Uses Services and Emergency Care Data Set

Infections

n = 43,338 COVID-19-positive patients

Most patients were unvaccinated, 32,078 (74·0)

Median age 31, (IQR, 17 – 42)

Delta = 8,682

Alpha = 34,656

Admitted to hospital or sought emergency care within 14 days of positive test

Delta = 498 (5.7%)

Alpha = 1,448 (4·2%)

Adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination status

HR for attendance at emergency care or hospitalisation = 1.45

HR for hospital admission = 2.26

In the subgroup of vaccinated patients

No significant difference between variants for emergency visit or hospitalisation

Interpretation

This large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant.

Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant.

PHE studies and protection against hospital admission

96% for the Pfizer-BioNTech vaccin

92% for the Oxford-AstraZeneca vaccine

UK rates

47.9 million people, (88%) aged 16 and over, first dose of a vaccine

42 million people, (78%) aged 16 and over, have had a second

Dr Gavin Dabrera, PHE

We already know that vaccination offers excellent protection against Delta and, as this variant accounts for over 99% of Covid cases in the UK, it is vital that those who have not received two doses of vaccine do so as soon as possible

It is still important that if you have Covid symptoms, stay home and get a PCR test as soon as possible

Lancet study findings are consistent with Scottish data

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Comparing Alpha and Delta risks.

USA, MAB therapy

FDA, EUA

Florida, 21 popup sites

(via injection shots)

Dr. Fauci, can reduce deaths by 85%

If early enough in the infection

Lowers viral load

Texas, Missouri, Iowa

Observe for one hour