Dr Josh Axe
@drjoshaxe·2.6M subscribers·2.8K videos
Ancient Longevity Secrets: How to Activate Autophagy with a 72-Hour Fast | Dr. Josh Axe
Posted
May 4, 2026
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May 4, 2026
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31:50Now PlayingFasting is one of the most powerful healing practices in human history—it’s free, requires zero equipment, and your body is literally designed for it. But while it sounds simple, there is a wrong way to do it, especially when it comes to the hormonal "engine switch" that happens in the first 24 hours. In this episode, I walk you through exactly what happens in your body during a 3-day fast, from clearing out "zombie cells" to the 60% drop in aging markers.
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Timestamps
Insulin drop during fastingMolecular Metabolism
Glycogen storageCleveland Clinic
Ghrelin and meal timingDiabetes Journal
Growth hormone 14x studyFrontiers in Endocrinology
Ketones and brain energyAnnals of Medicine
Nobel Prize Autophagy (Ohsumi)
Insulin resistance prevalenceStatPearls / NCBI
Immune stem cell resetUSC Valter Longo Lab
Muscle loss during fastingNutrients
Food addiction dataMichigan Medicine
The Didache (c. 100 AD): Chapter 8
DISCLAIMER
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
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