Next Up with Mark Halperin
Next Up with Mark Halperin
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Gavin Newsom’s New Playbook, Democratic Voter Decline, and Fighting Cancer with Michael Caputo

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August 21, 2025

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Mark opens the show with his reported monologue on why and how Gavin Newsom is so misunderstood. He explains why Newsom stands alone in the Democratic Party’s top tier of potential presidential candidates for 2028 due to his focus on the “Three As”: action, attention-getting, and authenticity. Mark also corrects four myths about Newsom, including the possibility that the California governor may never actually run for president.

Then former Senator Mark Pryor (D-Arkansas) joins the program to assess the Democratic Party’s structural challenges. From donor defections and the rise of billionaires and Super PACs on the Republican side to declining voter registration, Pryor warns that Democrats must engage with the grassroots. He argues the party must urgently refocus on organizing, messaging, and turnout if it hopes to compete in 2028. Plus, his candid advice on what it will take to reverse the Democratic Party’s downward slide.

Finally, Michael Caputo shares a deeply personal account of battling cancer and cancellation at the same time — and how it fuels his support for the MAHA movement. He stresses the importance of President Trump and Robert F. Kennedy Jr. prioritizing childhood cancer, chronic disease, and the use of AI in medical breakthroughs. Caputo also explains why early-onset cancer is rising at alarming rates – and why he believes this fight must be at the center of America’s health agenda.

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Guests & Subjects Covered

Gavin NewsomDemocratic PartysThree AsSenator Mark Pryor D-ArkansasSuper PACsFinally Michael CaputoPresident TrumpRobert F Kennedy Jr

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Gavin Newsom’s New Playbook, Democratic Voter Decline, and Fighting Cancer with Michael Caputo · Megyn Kelly · Sentinel