Professor Dave Explains
Professor Dave Explains
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Mannich Reaction

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September 9, 2021

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One of the most important name reactions is the Mannich reaction, named after German chemist Carl Mannich, who developed it in 1912. In its original form, this takes formaldehyde, an enolizable ketone, and a secondary amine, and produces a molecule with both ketone and amine functionality. Let's take a look at the mechanism of this reaction and some of its applications.

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Mannich Reaction · Professor Dave Explains · Sentinel