Essentials: Erasing Fears & Traumas Using Modern Neuroscience
In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses.
November 6, 2025
40 min
Full
352 of 417

November 6, 2025
Essentials: Erasing Fears & Traumas Using Modern Neuroscience
0:00 / 40:00
Excerpt playback isn’t available for this episode — use the full-episode link.
Search the Record
Moment search isn’t open for this episode yet
When it opens, you’ll be able to type any phrase and jump straight to the second it was said.
Andrew Huberman Episodes Around November 6, 2025
Episode 352 of 417 — walk the feed in the order it was published.
40:00This episodeEssentials: Erasing Fears & Traumas Using Modern Neuroscience
Summary
In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses.
I explain why successful fear treatment requires both extinction of the old fearful response and replacement with a new positive association—not just cognitive reframing. I also explain how the threat reflex activates specific circuits connecting the amygdala, prefrontal cortex, and dopamine systems, and why detailed recounting of traumatic events progressively reduces their physiological impact. Finally, I review evidence-based approaches, including prolonged exposure therapy and cognitive behavioral therapy, discuss how five minutes per day of deliberate stress through cyclic hyperventilation can rewire fear responses, explain the critical role of social connection in activating neural pathways that reduce trauma, and share supplementation options for managing anxiety.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
AGZ by AG1: https://drinkagz.com/huberman
LMNT: https://drinklmnt.com/huberman
Function: https://functionhealth.com/huberman
Timestamps
(0:00) Introducing Fear & Trauma
(0:17) What is Fear?
(1:03) Autonomic Arousal: "Alertness" vs. "Calmness"
(2:05) Fear vs. Stress & Anxiety
(9:20) "The Threat Reflex": Neural Circuits for Fear
(20:50) Cognitive (Narrative) Therapies for Fear
(26:35) PTSD Treatments: Ketamine, MDMA, Oxytocin
(33:11) Deliberate Brief Stress Can Erase Fears & Trauma
(35:51) Nutrition, Sleep, & Other General Support Erasing Fear & Trauma
(38:18) Recap
Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode details and artwork are published by the show’s own feed. Sentinel plays short cited excerpts and links every episode back to its publisher.














