Dr John Campbell
@campbellteaching·3.3M subscribers·3.1K videos
CDC leak, summary and full report
Posted
July 31, 2021
Views
1,147,266
Likes
20,260
Comments
11,965
Engagement
2.81%
July 31, 2021
1,147,266
20,260
11,965
2.81%
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29:36Now PlayingSorry, had to reupload this video, its the same as the poorly uploaded previous version. United States, Delta variant, acknowledge the war has changed
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Summary, Delta is different from previous strains
Highly contagious
Likely more severe
Breakthrough infections may be as transmissible as unvaccinated cases
Vaccines prevent more than 90% of severe disease, but may be less effective at preventing infection or transmission
Therefore, more breakthrough and more community spread despite vaccination
NPIs are essential to prevent continued spread with current vaccine coverage
Vaccine breakthrough cases may reduce public confidence in vaccines
Vaccine breakthrough cases are expected
Will increase as a proportion of total cases as vaccine coverage increases
Vaccine breakthrough cases will occur more frequently in congregate settings
and in groups at risk of primary vaccine failure (i.e., immune compromised, elderly)
Communication challenges have been associated with increasing proportions of cases vaccinated even when vaccine effectiveness (VE) remains stable
Important to update communications describing breakthrough cases as “rare” or as a “small percentage” of cases
35,000 symptomatic infections per week with 162 million vaccinated
December 14, 2020 – April 10, 2021
Vaccine effectiveness against infection, 91% among fully vaccinated; 81% for partially vaccinated
40% lower mean RNA viral load
Shorter mean duration of detectable viral RNA (2.7 v. 8.9 days)
Lower risk of febrile symptoms (25.0% v. 63.1%)
Shorter mean duration of symptoms (10.3 v. 16.7 days)
Vaccine effectiveness against hospitalization 88%
No evidence of waning immunity through 20 weeks post-2nd dose
Lower estimates of VE for mRNA vaccines among immunocompromised populations
After 2 doses, 59 - 80% against infection
Vaccines more effective against hospitalization/death illness infection
Delta infections associated with higher viral load and duration of shedding
India
Lower cycle threshold (Ct) values in Delta breakthrough cases
HCW, Ct 16.5
Non delta, Ct 19
Delta infection associated with longer duration of Ct values less than 30 18 days vs. 13 days for ancestral strains
Delta variant vaccine breakthrough cases may be as transmissible as unvaccinated cases
UK, Cases down a bit today
Includes lateral flow tests
Saturday, 31st +
Friday, 30th + 29,622
Thursday, 29th + 31,117
Wednesday, 28th + 27,734
Seven days of decline
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