Dr John Kruse
@drjohnkruse·16.8K subscribers·484 videos
Weekly Q&A: Amlodipine for ADHD? / Body Focused Repetitive Behaviors
Posted
October 15, 2025
Views
311
Likes
12
Comments
8
Engagement
6.43%
October 15, 2025
311
12
8
6.43%
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27:59Now PlayingJoin me for my Weekly Mental Health Recap and Q&A!
Livestream every Tuesday at 10:00am West Coast USA / 1:00pm East Coast USA / 7:00am Hawaii / 7:00pm Central European
Videos released this week:
- Amlodipine for ADHD?
- Body Focused Repetitive Behaviors and ADHD
After a 1 minute recap of each video, I’ll be available for questions on these topics or any other related to Mental Health.
- Amlodipine for ADHD?:
Harvard researcher Bruce Yankner and colleagues recently released a set of studies demonstrating that the calcium channel blocking, blood pressure lowering medication amlodipine may be helpful for ADHD. In animal models of ADHD (specific genetic strains of zebrafish and rats) amlodipine decreased hyperactivity and impulsivity. Amlodipine does get into the brain, and affects the activation of certain genes in the brain. Complex genetic studies suggest that amlodipine could help with ADHD through its effects on calcium channel proteins, and that individuals taking amlodipine may display fewer ADHD symptoms. But we're still waiting for direct studies giving amlodipine to individuals with ADHD.
- Body Focused Repetitive Behaviors and ADHD:
Hairpulling, skin picking, and nail biting are among the most common body focused repetitive behaviors. These behaviors appear to have similarities to social grooming behaviors in rodents and primates. Although formerly associated with Obsessive Compulsive Disorder (OCD), BFRB appears to more closely connected to the impulsivity of ADHD. New research suggests that glutamate blocking or modulating medications and supplements such as memantine, or N-Acetylcysteine (NAC) may be helpful in treating BFRB.
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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions.
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