Andrew Huberman
@hubermanlab·7.5M subscribers·510 videos
Journal Club with Dr. Peter Attia | Effects of Light & Dark on Mental Health & Treatments for Cancer
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January 22, 2024
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3:08:32Now PlayingIn this journal club episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins-trained physician focusing on healthspan and lifespan and the host of The Drive podcast.
We each present a peer-reviewed scientific paper chosen because it contains novel, interesting, and actionable data. First, we discuss a paper on how bright light exposure at sunrise and throughout the day and dark exposure at night independently improve mental health and can offset some of the major symptoms of mental health disorders such as depression and anxiety. Then, we discuss an article that explores a novel class of immunotherapy treatments to combat cancer. We also discuss some of the new data on low-calorie sweeteners and if they are safe. This episode should be of interest to listeners curious about maximizing their vitality and longevity and to anyone seeking science-supported ways to improve mental health and lifespan.
Thank you to our sponsors
Eight Sleep
Dr. Peter Attia
The Drive Podcast
Early Medical
Journal Articles
Day and night light exposure are associated with psychiatric disordersan objective light study in greater than 85,000 people (first article discussed)
Early evening light mitigates sleep compromising physiological and alerting responses to subsequent late evening light
Absence of Circadian Phase Resetting in Response to Bright Light Behind the Knees
Time spent in outdoor light is associated with mood, sleep, and circadian rhythmrelated outcomesA crosssectional and longitudinal study in over 400,000 UK Biobank participants
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma (second article discussed)
Understanding the Warburg EffectThe Metabolic Requirements of Cell Proliferation
Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
Autoimmunity Correlates With Tumor Regression in Patients With Metastatic Melanoma Treated With AntiCytotoxic TLymphocyte Antigen4
Other Resources
Light Meter app (Google Play)
Light Meter app (App Store)
Fluorescence & Mammals
Dr. Alia CrumScience of Mindsets for Health & Performance
Sugar Substitutes
The mechanisms of action for immune checkpoint inhibitors
Timestamps
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