Dr John Kruse
@drjohnkruse·16.8K subscribers·484 videos
Weekly Q&A: Cortisol and ADHD
Posted
March 11, 2026
Views
411
Likes
31
Comments
10
Engagement
9.98%
March 11, 2026
411
31
10
9.98%
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1:02:43Now PlayingJoin me for my Weekly Mental Health Recap and Q&A!
Livestream every Tuesday at 9:00am West Coast USA / 12:00pm East Coast USA / 6:00am Hawaii / 5:00pm Central European
Video released this week:
- Cortisol and ADHD
After a 1 minute recap of the video, I’ll be available for questions on this topic or any other related to Mental Health.
- Cortisol and ADHD - Tired? It's Not Adrenal Fatigue:
Circadian rhythms influence cortisol release but it is also pumped out by the adrenal gland (along with norepinephrine and epinephrine) in response to stress. Cortisol helps make more glucose available to muscles and fat cells; damps down inflammation; and affects the brain.
Many mental health conditions are associated with abnormal cortisol rhythms and abnormal responses to stress. Meta-analyses indicate for those with ADHD, cortisol levels are suppressed throughout the circadian cycle, but then show unusually robust responses to stress. However, individuals with ADHD show a great deal of variation, and unusual patterns of cortisol release seem more related to co-occurring conditions rather than to ADHD itself. While prolonged, elevated cortisol release can have damaging effects on the hippocampus, amygdala, and immune functions, evidence does not support the existence of “adrenal fatigue” in which the adrenal gland “burns out” and fails to make enough cortisol.
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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions.
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