Dr John Kruse
@drjohnkruse·16.8K subscribers·484 videos
ADHD and the Amygdala
Posted
January 1, 2026
Views
946
Likes
70
Comments
13
Engagement
8.77%
January 1, 2026
946
70
13
8.77%
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15:52Now PlayingMain Chapters:
One of the earliest findings (1888) in neuroscience research was that the tip of the temporal lobe, containing the amygdala, was involved in processing fear and anger in monkeys. For decades the amygdala, an almond-shaped structure that sits immediately in front of the hippocampus, on each side of the brain, has been recognized at intimately involved in the limbic system which generates, regulates and expresses emotions. In particular, the amygdalae integrate the processing of rewards and emotion, and help store emotional memories.
The prefrontal cortex plays a prominent role in symptoms of ADHD, but in recent years brain imaging and activation research has implicated other brain structures, including the amygdala. Although the studies are not completely consistent, those with ADHD appear to have smaller amygdala that differ in how they are connected to other brain regions.
A small number of studies, using different approaches, show that amygdala activity correlates with emotional dysregulation in those with ADHD. Stimulant medications, as well asa EEG-biofeedback treatments, appear to decrease amygdala hyperactivity when they improve emotional processing.
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Free link to my Medium Article on ADHD and the Amygdala:
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References:
Pilot Study of Prism EFP NeuroFeedback in Adult ADHD (2024)
Meta-analysis reveals a reduced surface area of the amygdala in individuals with attention deficit/hyperactivity disorder (2023)
Associations of Irritability With Functional Connectivity of Amygdala and Nucleus Accumbens in Adolescents and Young Adults With ADHD (2022)
Integrity of Amygdala Subregion-Based Functional Networks and Emotional Lability in Drug-Naïve Boys With ADHD (2020)
Amygdala Abnormalities in Adults With ADHD (2019)
Correlation between amygdala volume and impulsivity in adults with attention-deficit hyperactivity disorder (2015)
Full Chapter list:
Streamed live July 30, 2024
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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions.
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